About us

Our research team focuses on elucidating the role of intrinsically disordered proteins (IDPs) in biology. In particular, we are interested in the mitogen-activated protein kinase (MAPK) cell signaling pathways and how intrinsically disordered scaffold proteins regulate signaling specificity and MAPK activity. We use NMR spectroscopy combined with X-ray crystallography and biophysics to study these dynamic assemblies at atomic resolution.

Latest news

12/2025 Our paper on hierarchical folding-upon-binding of an intrinsically disordered protein is out in Nature Communications. Work led by Ph.D. student and postdoc Lenette Kjaer, in collaboration with Andrés Palencia and Guillaume Bouvignies.

12/2025 Michal Buša joins the group as an Impulscience postdoctoral fellow.

06/2025 Our paper on multi-site phosphorylation of the scaffold protein JIP1 and the role of kinase docking site interactions is out in Advanced Science. Work led by postdoc Thibault Orand in collaboration with Pau Bernadó and Juan Cortés.

02/2025 Our work on the intrinsically disordered scaffold protein JIP1 and its bipartite interaction with the kinase JNK1 is out in PNAS. Work led by postdocs Thibault Orand and Elise Delaforge in collaboration with the Palencia and Davis groups.

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