07/2022 Join us! Several positions are now open to join our team.
07/2022 We are grateful to the Agence National de la Recherche (ANR) for funding an exciting project with the groups of Dr. Andres Palencia and Prof. Vincent Cattoir. We will be developing new drugs against pathogenic gram-positive bacteria to fight antibiotic resistance.
02/2022 How can aromatic residues undergo ring flipping in the core of a protein despite engaging in multiple stabilizing interactions to maintain protein fold? Read our new publication in Nature where we reveal the structural changes associated with ring flipping of a core tyrosine. Work led by postdoc Laura Mariño in collaboration with the Palencia group.
01/2022 Our study on the interaction of the SARS-CoV-2 nucleoprotein with its viral partner nsp3a is out in Science Advances. Work in collaboration with the Blackledge team.
08/2021 How can IDPs fold into two different conformations upon binding to different protein targets while keeping the same binding affinity? The key is enthalpy-entropy compensation. Read our new publication here.
07/2021 We are grateful to the Agence National de la Recherche (ANR) for funding our team for 4 years through the ANR collaborative projects call. We are teaming up with the group of Dr. Andres Palencia.
10/2020 Lenette Frøsig Kjær joins the team as a Ph.D. student
08/2020 Our recent paper describing the molecular mechanisms underlying the switch from the lysogenic to the lytic state in a temperate bacteriophage is out in PNAS. A nice collaboration with the groups of Prof. Leila Lo Leggio (University of Copenhagen) and Dr. Mogens Kilstrup (Technical University of Denmark).
03/2020 We are grateful to the Grenoble Alliance for Integrated Structural & Cell Biology (GRAL) for awarding a Ph.D. fellowship to the team
01/2020 Laura Mariño Pérez joins the team as an FRM postdoctoral fellow
01/2020 We are grateful to the Fondation Innovation en Infectiologie (FINOVI) for awarding funding for a collaborative project with Andrés Palencia’s group at the Institute for Advanced Biosciences (IAB)
10/2019 Laura Mariño Pérez is awarded a 3-year postdoctoral fellowship from the Fondation pour la Recherche Medicale (FRM)
10/2019 Thibault Orand joins the team as a Ph.D. student
06/2019 Thibault Orand is awarded a Ph.D. fellowship from the Université Grenoble Alpes
06/2019 Luiza Mamigonian Bessa joins the team as an ANR postdoctoral fellow
03/2019 Visiting Ph.D. student Laura Mariño Pérez, University of Balearic Islands Spain, joins the team for 3 months to study protein dynamics by NMR
01/2019 Thibault Orand joins the team as a master (M2) student
01/2019 Our paper on site-specific dynamics of an IDP complex is selected to feature in the J. Am. Chem. Soc. Young Investigator Virtual Issue 2019 that compiles outstanding work of young investigators published in J. Am. Chem. Soc. in 2018
01/2019 Our review on studying binding mechanisms and dynamics of IDP complexes is out in Curr. Opin. Struct. Biol.
05/2018 We are grateful to the Agence National de la Recherche (ANR) for funding our team for 2 years through the ANR-Tremplin-ERC call
01/2018 Our latest paper on mapping site-specific dynamics of an IDP on the surface of a partner protein is out in J. Am. Chem. Soc. A nice collaboration with the IAB Grenoble and the ENS Paris.